Prophylaxis Against Respiratory Syncytial Virus in High-Risk Infants

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Abstract of Journal Article - May 2000   

By Gilbert Handal, MD; Marie-Martine Logvinoff, MD; Narcedallia Zegarra, MD; Luz Allen, MD; Antonio Jesurun, MD; Garrett Levin, MD; Aye Thida, MD

Hospitalizations secondary to respiratory syncytial virus (RSV) infection in children were monitored before and after the administration of RSV immune globulin. Monitored also was the effectiveness of prophylaxis in preventing the disease among at-risk children along the Texas-Mexico border. Small premature infants were at the greatest risk of hospitalization; preterm infants and then term infants followed. Prophylaxis does not necessarily prevent RSV bronchiolitis but may reduce the severity of the pulmonary disease.

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